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PRMT5 regulates cell pyroptosis by silencing CASP1 in multiple myeloma

Protein arginine methyltransferase 5 (PRMT5), a histone methyltransferase responsible for the symmetric dimethylation of histone H4 on Arg 3 (H4R3me2s), is an enzyme that participates in tumor cell progression in a variety of hematological malignancies. However, the biological functions of PRMT5 in...

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Detalles Bibliográficos
Autores principales: Xia, Tian, Liu, Ming, Zhao, Quan, Ouyang, Jian, Xu, Peipei, Chen, Bing
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group UK 2021
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8445991/
https://www.ncbi.nlm.nih.gov/pubmed/34531375
http://dx.doi.org/10.1038/s41419-021-04125-5