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Oxidative stress-induced impairment of trophoblast function causes preeclampsia through the unfolded protein response pathway

Pre-eclampsia (PE) is a pregnancy-specific disorder, characterized by hypertension and proteinuria. In PE, trophoblasts mediated inadequate remodeling of uterine spiral arteries seem to interrupt uteroplacental blood flow, one of the hallmarks in the early onset of PE (EO-PE). This, in turn, results...

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Detalles Bibliográficos
Autores principales: Mukherjee, Indrani, Dhar, Ruby, Singh, Sunil, Sharma, Jai Bhagwan, Nag, Tapas Chandra, Mridha, Asit Ranjan, Jaiswal, Parul, Biswas, Subhrajit, Karmakar, Subhradip
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group UK 2021
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8446002/
https://www.ncbi.nlm.nih.gov/pubmed/34531444
http://dx.doi.org/10.1038/s41598-021-97799-y