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Tissue Specific DNA Repair Outcomes Shape the Landscape of Genome Editing

The use of Clustered Regularly Interspaced Short Palindromic Repeats (CRISPR)-Cas9 has moved from bench to bedside in less than 10years, realising the vision of correcting disease through genome editing. The accuracy and safety of this approach relies on the precise control of DNA damage and repair...

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Detalles Bibliográficos
Autores principales: Meyenberg, Mathilde, Ferreira da Silva, Joana, Loizou, Joanna I.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Frontiers Media S.A. 2021
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8446275/
https://www.ncbi.nlm.nih.gov/pubmed/34539755
http://dx.doi.org/10.3389/fgene.2021.728520