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Bayesian variable selection with a pleiotropic loss function in Mendelian randomization

Mendelian randomization is the use of genetic variants as instruments to assess the existence of a causal relationship between a risk factor and an outcome. A Mendelian randomization analysis requires a set of genetic variants that are strongly associated with the risk factor and only associated wit...

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Detalles Bibliográficos
Autores principales: Gkatzionis, Apostolos, Burgess, Stephen, Conti, David V., Newcombe, Paul J.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: 2021
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8446304/
https://www.ncbi.nlm.nih.gov/pubmed/34155684
http://dx.doi.org/10.1002/sim.9109