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The Slit‐binding Ig1 domain is required for multiple axon guidance activities of Drosophila Robo2

Drosophila Robo2 is a member of the evolutionarily conserved Roundabout (Robo) family of axon guidance receptors. Robo receptors signal midline repulsion in response to Slit ligands, which bind to the N‐terminal Ig1 domain in most family members. In the Drosophila embryonic ventral nerve cord, Robo1...

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Detalles Bibliográficos
Autores principales: Howard, LaFreda J., Reichert, Marie C., Evans, Timothy A.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: John Wiley & Sons, Inc. 2021
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8446337/
https://www.ncbi.nlm.nih.gov/pubmed/34411419
http://dx.doi.org/10.1002/dvg.23443