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NLRP3 Inflammasome-Dependent Increases in High Mobility Group Box 1 Involved in the Cognitive Dysfunction Caused by Tau-Overexpression

Tau hyperphosphorylation is a characteristic alteration present in a range of neurological conditions, such as traumatic brain injury (TBI) and neurodegenerative diseases. Treatments targeting high-mobility group box protein 1 (HMGB1) induce neuroprotective effects in these neuropathologic condition...

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Detalles Bibliográficos
Autores principales: Zhao, Yan, Tan, Si-Wei, Huang, Zhi-Zhong, Shan, Fa-Bo, Li, Ping, Ning, Ya-Lei, Ye, Shi-Yang, Zhao, Zi-Ai, Du, Hao, Xiong, Ren-Ping, Yang, Nan, Peng, Yan, Chen, Xing, Zhou, Yuan-Guo
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Frontiers Media S.A. 2021
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8446370/
https://www.ncbi.nlm.nih.gov/pubmed/34539383
http://dx.doi.org/10.3389/fnagi.2021.721474