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Neurofilament Light Chain and Intermediate HTT Alleles as Combined Biomarkers in Italian ALS Patients

OBJECTIVE: To study the possible implication of the two biomarkers, intermediate alleles (IAs) of the Huntingtin (HTT) gene and neurofilament light chain (NfL) levels in plasma, in amyotrophic lateral sclerosis (ALS) patients. METHODS: We analyzed IAs in a cohort of 106 Italian ALS patients and meas...

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Detalles Bibliográficos
Autores principales: Ingannato, Assunta, Bagnoli, Silvia, Mazzeo, Salvatore, Bessi, Valentina, Matà, Sabrina, Del Mastio, Monica, Lombardi, Gemma, Ferrari, Camilla, Sorbi, Sandro, Nacmias, Benedetta
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Frontiers Media S.A. 2021
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8446383/
https://www.ncbi.nlm.nih.gov/pubmed/34539331
http://dx.doi.org/10.3389/fnins.2021.695049