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Neurofilament Light Chain and Intermediate HTT Alleles as Combined Biomarkers in Italian ALS Patients
OBJECTIVE: To study the possible implication of the two biomarkers, intermediate alleles (IAs) of the Huntingtin (HTT) gene and neurofilament light chain (NfL) levels in plasma, in amyotrophic lateral sclerosis (ALS) patients. METHODS: We analyzed IAs in a cohort of 106 Italian ALS patients and meas...
Autores principales: | Ingannato, Assunta, Bagnoli, Silvia, Mazzeo, Salvatore, Bessi, Valentina, Matà, Sabrina, Del Mastio, Monica, Lombardi, Gemma, Ferrari, Camilla, Sorbi, Sandro, Nacmias, Benedetta |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Frontiers Media S.A.
2021
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8446383/ https://www.ncbi.nlm.nih.gov/pubmed/34539331 http://dx.doi.org/10.3389/fnins.2021.695049 |
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