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Integrated pan‐cancer of AURKA expression and drug sensitivity analysis reveals increased expression of AURKA is responsible for drug resistance

INTRODUCTION: The AURKA gene encodes a protein kinase involved in cell cycle regulation and plays an oncogenic role in many cancers. The main objective of this study is to analyze AURKA expression in 13 common cancers and its role in prognostic and drug resistance. METHOD: Using the cancer genome at...

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Detalles Bibliográficos
Autores principales: Miralaei, Noushin, Majd, Ahmad, Ghaedi, Kamran, Peymani, Maryam, Safaei, Masoomeh
Formato: Online Artículo Texto
Lenguaje:English
Publicado: John Wiley and Sons Inc. 2021
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8446408/
https://www.ncbi.nlm.nih.gov/pubmed/34337875
http://dx.doi.org/10.1002/cam4.4161