The First Chemically-Synthesised, Highly Immunogenic Anti-SARS-CoV-2 Peptides in DNA Genotyped Aotus Monkeys for Human Use

Thirty-five peptides selected from functionally-relevant SARS-CoV-2 spike (S), membrane (M), and envelope (E) proteins were suitably modified for immunising MHC class II (MHCII) DNA-genotyped Aotus monkeys and matched with HLA-DRβ1* molecules for use in humans. This was aimed at producing the first...

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Detalles Bibliográficos
Autores principales: Patarroyo, Manuel E., Patarroyo, Manuel A., Alba, Martha P., Pabon, Laura, Rugeles, María T., Aguilar-Jimenez, Wbeimar, Florez, Lizdany, Bermudez, Adriana, Rout, Ashok K., Griesinger, Christian, Suarez, Carlos F., Aza-Conde, Jorge, Reyes, César, Avendaño, Catalina, Samacá, Jhoan, Camargo, Anny, Silva, Yolanda, Forero, Martha, Gonzalez, Edgardo
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Frontiers Media S.A. 2021
Materias:
Immunology
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8446425/
https://www.ncbi.nlm.nih.gov/pubmed/34539660
http://dx.doi.org/10.3389/fimmu.2021.724060

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8446425/
https://www.ncbi.nlm.nih.gov/pubmed/34539660
http://dx.doi.org/10.3389/fimmu.2021.724060

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