Cargando…

The First Chemically-Synthesised, Highly Immunogenic Anti-SARS-CoV-2 Peptides in DNA Genotyped Aotus Monkeys for Human Use

Thirty-five peptides selected from functionally-relevant SARS-CoV-2 spike (S), membrane (M), and envelope (E) proteins were suitably modified for immunising MHC class II (MHCII) DNA-genotyped Aotus monkeys and matched with HLA-DRβ1* molecules for use in humans. This was aimed at producing the first...

Descripción completa

Detalles Bibliográficos
Autores principales:	Patarroyo, Manuel E., Patarroyo, Manuel A., Alba, Martha P., Pabon, Laura, Rugeles, María T., Aguilar-Jimenez, Wbeimar, Florez, Lizdany, Bermudez, Adriana, Rout, Ashok K., Griesinger, Christian, Suarez, Carlos F., Aza-Conde, Jorge, Reyes, César, Avendaño, Catalina, Samacá, Jhoan, Camargo, Anny, Silva, Yolanda, Forero, Martha, Gonzalez, Edgardo
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	Frontiers Media S.A. 2021
Materias:	Immunology
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8446425/ https://www.ncbi.nlm.nih.gov/pubmed/34539660 http://dx.doi.org/10.3389/fimmu.2021.724060

Ejemplares similares

Characterising a Microsatellite for DRB Typing in Aotus vociferans and Aotus nancymaae (Platyrrhini)
por: López, Carolina, et al.
Publicado: (2014)

Identification and Diversity of Killer Cell Ig-Like Receptors in Aotus vociferans, a New World Monkey
por: Garzón-Ospina, Diego, et al.
Publicado: (2013)

Stereo electronic principles for selecting fully-protective, chemically-synthesised malaria vaccines
por: Patarroyo, Manuel E., et al.
Publicado: (2022)

SM-COLSARSPROT: Highly Immunogenic Supramutational Synthetic Peptides Covering the World’s Population
por: Patarroyo, Manuel A., et al.
Publicado: (2022)

IMPIPS: The Immune Protection-Inducing Protein Structure Concept in the Search for Steric-Electron and Topochemical Principles for Complete Fully-Protective Chemically Synthesised Vaccine Development
por: Patarroyo, Manuel Elkin, et al.
Publicado: (2015)

3D Analysis of the TCR/pMHCII Complex Formation in Monkeys Vaccinated with the First Peptide Inducing Sterilizing Immunity against Human Malaria
por: Patarroyo, Manuel A., et al.
Publicado: (2010)

Owl Monkey Alu Insertion Polymorphisms and Aotus Phylogenetics
por: Storer, Jessica M., et al.
Publicado: (2022)

Loop-Mediated Isothermal Amplification as Point-of-Care Diagnosis for Neglected Parasitic Infections
por: Avendaño, Catalina, et al.
Publicado: (2020)

Identification, classification and evolution of Owl Monkeys (Aotus, Illiger 1811)
por: Menezes, Albert N, et al.
Publicado: (2010)

Specific β-Turns Precede PPII(L) Structures Binding to Allele-Specific HLA-DRβ1(*) PBRs in Fully-Protective Malaria Vaccine Components
por: Bermudez, Adriana, et al.
Publicado: (2018)

A Comprehensive Review of the Immunological Response against Foot-and-Mouth Disease Virus Infection and Its Evasion Mechanisms
por: Rodríguez-Habibe, Ibett, et al.
Publicado: (2020)

Mycobacterium tuberculosis Rv0679c protein sequences involved in host-cell infection: Potential TB vaccine candidate antigen
por: Cifuentes, Diana P, et al.
Publicado: (2010)

An Unusual Karyotypic Observation on Cultured Cells from an Owl Monkey (Aotus Trivirgatus)
por: Jarvis, J. E.
Publicado: (1974)

Mechanisms Associated with Trypanosoma cruzi Host Target Cell Adhesion, Recognition and Internalization
por: Rodríguez-Bejarano, Oscar Hernán, et al.
Publicado: (2021)

Moonstruck Primates: Owl Monkeys (Aotus) Need Moonlight for Nocturnal Activity in Their Natural Environment
por: Fernández-Duque, Eduardo, et al.
Publicado: (2010)

Immunogenicity of a chimeric Plasmodium falciparum merozoite surface protein vaccine in Aotus monkeys
por: Burns, James M., et al.
Publicado: (2016)

Histocytological specificities of adrenal cortex in the New World Monkeys, Aotus lemurinus and Saimiri boliviensis
por: TACHIBANA, Toru, et al.
Publicado: (2015)

A malaria vaccine protects Aotus monkeys against virulent Plasmodium falciparum infection
por: Srinivasan, Prakash, et al.
Publicado: (2017)

Comparing Class II MHC DRB3 Diversity in Colombian Simmental and Simbrah Cattle Across Worldwide Bovine Populations
por: Ordoñez, Diego, et al.
Publicado: (2022)

Preliminary Evaluation of the Safety and Immunogenicity of an Antimalarial Vaccine Candidate Modified Peptide (IMPIPS) Mixture in a Murine Model
por: Lambraño, Jennifer, et al.
Publicado: (2019)

Effective treatment with a tetrandrine/chloroquine combination for chloroquine-resistant falciparum malaria in Aotus monkeys
por: Ye, Zuguang, et al.
Publicado: (2013)

Susceptibility and lack of evidence for a viremic state of rabies in the night owl monkey, Aotus nancymaae
por: Reaves, Erik J, et al.
Publicado: (2012)

Using the PfEMP1 Head Structure Binding Motif to Deal a Blow at Severe Malaria
por: Patarroyo, Manuel E., et al.
Publicado: (2014)

A Large Size Chimeric Highly Immunogenic Peptide Presents Multistage Plasmodium Antigens as a Vaccine Candidate System against Malaria
por: Lozano, José Manuel, et al.
Publicado: (2017)

269. Reference Data of Biochemical and Hematology Parameters in Juvenile and Adult Owl Monkeys (Aotus nancymaae) for Biomedical Research
por: Carlos Gaspar, Juan, et al.
Publicado: (2023)

Specific Binding Peptides from Rv3632: A Strategy for Blocking Mycobacterium tuberculosis Entry to Target Cells?
por: Sánchez-Barinas, Christian David, et al.
Publicado: (2019)

Low genetic diversity in the locus encoding the Plasmodium vivax P41 protein in Colombia’s parasite population
por: Forero-Rodríguez, Johanna, et al.
Publicado: (2014)

Low genetic diversity and functional constraint in loci encoding Plasmodium vivax P12 and P38 proteins in the Colombian population
por: Forero-Rodríguez, Johanna, et al.
Publicado: (2014)

Heterogeneous genetic diversity pattern in Plasmodium vivax genes encoding merozoite surface proteins (MSP) -7E, −7F and -7L
por: Garzón-Ospina, Diego, et al.
Publicado: (2014)

Evidence of functional divergence in MSP7 paralogous proteins: a molecular-evolutionary and phylogenetic analysis
por: Garzón-Ospina, Diego, et al.
Publicado: (2016)

Owl Monkeys (Aotus nigriceps and A. infulatus) Follow Routes Instead of Food-Related Cues during Foraging in Captivity
por: da Costa, Renata Souza, et al.
Publicado: (2014)

Plasmodium falciparum Blood Stage Antimalarial Vaccines: An Analysis of Ongoing Clinical Trials and New Perspectives Related to Synthetic Vaccines
por: Salamanca, David Ricardo, et al.
Publicado: (2019)

Plasmodium falciparum pre-erythrocytic stage vaccine development
por: Molina-Franky, Jessica, et al.
Publicado: (2020)

Aislamiento y caracterización de una cepa temprana de SARS-CoV-2 durante la epidemia de 2020 en Medellín, Colombia
por: Díaz, Francisco J., et al.
Publicado: (2020)

The Hydroalcoholic Extract of Uncaria tomentosa (Cat's Claw) Inhibits the Infection of Severe Acute Respiratory Syndrome Coronavirus 2 (SARS-CoV-2) In Vitro
por: Yepes-Perez, Andres F., et al.
Publicado: (2021)

Genetic Diversity and Selection in Three Plasmodium vivax Merozoite Surface Protein 7 (Pvmsp-7) Genes in a Colombian Population
por: Garzón-Ospina, Diego, et al.
Publicado: (2012)

Can colour vision re-evolve? Variation in the X-linked opsin locus of cathemeral Azara’s owl monkeys (Aotus azarae azarae)
por: Mundy, N. I., et al.
Publicado: (2016)

A PfRH5-Based Vaccine Is Efficacious against Heterologous Strain Blood-Stage Plasmodium falciparum Infection in Aotus Monkeys
por: Douglas, Alexander D., et al.
Publicado: (2015)

The Cellular and Molecular Interaction Between Erythrocytes and Plasmodium falciparum Merozoites
por: Molina-Franky, Jessica, et al.
Publicado: (2022)

Strategies for developing multi-epitope, subunit-based, chemically synthesized anti-malarial vaccines
por: Patarroyo, M E, et al.
Publicado: (2008)

Cannot write session to /tmp/vufind_sessions/sess_7sr1eq2f3timnmjpv8c9ikolje