Cargando…

Thalidomide Suppresses Angiogenesis Through the Signal Transducer and Activator of Transcription 3/SP4 Signaling Pathway in the Peritoneal Membrane

Peritoneal angiogenesis is the key pathophysiological factor that limits peritoneal ultrafiltration during peritoneal dialysis (PD) in uremic patients. Thalidomide has been confirmed to inhibit angiogenesis by inhibiting the secretion of vascular endothelial growth factor (VEGF), but the exact mecha...

Descripción completa

Detalles Bibliográficos
Autores principales: Zhu, Nan, Wang, Ling, Guo, Huimin, Jia, Jieshuang, Gu, Lijie, Wang, Xuan, Yang, Man, Guan, Haochen, Yuan, Weijie
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Frontiers Media S.A. 2021
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8446434/
https://www.ncbi.nlm.nih.gov/pubmed/34539435
http://dx.doi.org/10.3389/fphys.2021.712147