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Polygenic Hazard Score Associated Multimodal Brain Networks Along the Alzheimer’s Disease Continuum

BACKGROUND: Late-onset Alzheimer’s disease (AD) is a polygenic neurodegenerative disease. Identifying the neuroimaging phenotypes behind the genetic predisposition of AD is critical to the understanding of AD pathogenesis. Two major questions which previous studies have led to are: (1) should the ge...

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Detalles Bibliográficos
Autores principales: Li, Kaicheng, Fu, Zening, Qi, Shile, Luo, Xiao, Zeng, Qingze, Xu, Xiaopei, Huang, Peiyu, Zhang, Minming, Calhoun, Vince D.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Frontiers Media S.A. 2021
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8446666/
https://www.ncbi.nlm.nih.gov/pubmed/34539385
http://dx.doi.org/10.3389/fnagi.2021.725246