Design, Synthesis, and Biological Evaluation of Benzo[cd]indol-2(1H)-ones Derivatives as a Lysosome-Targeted Anti-metastatic Agent

Lysosomes have become a hot topic in tumor therapy; targeting the lysosome is therefore a promising strategy in cancer therapy. Based on our previous lysosome-targeted bio-imaging agent, homospermine-benzo[cd]indol-2(1H)-one conjugate (HBC), we further developed three novel series of polyamine- benz...

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Detalles Bibliográficos
Autores principales: Li, Jinghua, Chen, Shuai, Zhao, Yancong, Gong, Huiyuan, Wang, Tong, Ge, Xiaoling, Wang, Yuxia, Zhu, Chenguang, Chen, Liang, Dai, Fujun, Xie, Songqiang, Wang, Chaojie, Luo, Wen
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Frontiers Media S.A. 2021
Materias:
Oncology
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8446683/
https://www.ncbi.nlm.nih.gov/pubmed/34540699
http://dx.doi.org/10.3389/fonc.2021.733589

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8446683/
https://www.ncbi.nlm.nih.gov/pubmed/34540699
http://dx.doi.org/10.3389/fonc.2021.733589

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