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MicroRNA-532-5p regulates oxidative stress and insulin secretion damage in high glucose-induced pancreatic β cells by downregulating the expression levels of CCND1

Diabetes mellitus is a metabolic disorder caused by insufficient insulin secretion. The expression of microRNA (miR)-532-5P is downregulated in diabetes, but its specific role in diabetes has not yet been elucidated. The present study aimed to investigate the specific mechanism underlying the effect...

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Detalles Bibliográficos
Autores principales: Zhong, Zhibiao, Su, Weilan, Chen, Hongmei
Formato: Online Artículo Texto
Lenguaje:English
Publicado: D.A. Spandidos 2021
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8446729/
https://www.ncbi.nlm.nih.gov/pubmed/34515323
http://dx.doi.org/10.3892/mmr.2021.12433