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Folded domain charge properties influence the conformational behavior of disordered tails

Intrinsically disordered proteins and protein regions (IDRs) make up around 30% of the human proteome where they play essential roles in dictating and regulating many core biological processes. While IDRs are often studied as isolated domains, in naturally occurring proteins most IDRs are found adja...

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Detalles Bibliográficos
Autores principales: Taneja, Ishan, Holehouse, Alex S.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Elsevier 2021
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8446786/
https://www.ncbi.nlm.nih.gov/pubmed/34557680
http://dx.doi.org/10.1016/j.crstbi.2021.08.002