Hepatic Regulator of G Protein Signaling 6 (RGS6) drives non-alcoholic fatty liver disease by promoting oxidative stress and ATM-dependent cell death

The pathophysiological mechanism(s) driving non-alcoholic fatty liver disease, the most prevalent chronic liver disease globally, have yet to be fully elucidated. Here, we identify regulator of G protein signaling 6 (RGS6), up-regulated in the livers of NAFLD patients, as a critical mediator of hepa...

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Detalles Bibliográficos
Autores principales: Mahata, Tarun, Sengar, Abhishek Singh, Basak, Madhuri, Das, Kiran, Pramanick, Arnab, Verma, Sumit Kumar, Singh, Praveen Kumar, Biswas, Sayan, Sarkar, Subhasish, Saha, Sudipta, Chatterjee, Suvro, Das, Madhusudan, Stewart, Adele, Maity, Biswanath
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Elsevier 2021
Materias:
Research Paper
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8446788/
https://www.ncbi.nlm.nih.gov/pubmed/34534913
http://dx.doi.org/10.1016/j.redox.2021.102105

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8446788/
https://www.ncbi.nlm.nih.gov/pubmed/34534913
http://dx.doi.org/10.1016/j.redox.2021.102105

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