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PROFICS: A bacterial selection system for directed evolution of proteases

Proteases serve as important tools in biotechnology and as valuable drugs or drug targets. Efficient protein engineering methods to study and modulate protease properties are thus of great interest for a plethora of applications. We established PROFICS (PRotease Optimization via Fusion-Inhibited Car...

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Detalles Bibliográficos
Autores principales: Kröß, Christina, Engele, Petra, Sprenger, Bernhard, Fischer, Andreas, Lingg, Nico, Baier, Magdalena, Öhlknecht, Christoph, Lier, Bettina, Oostenbrink, Chris, Cserjan-Puschmann, Monika, Striedner, Gerald, Jungbauer, Alois, Schneider, Rainer
Formato: Online Artículo Texto
Lenguaje:English
Publicado: American Society for Biochemistry and Molecular Biology 2021
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8446807/
https://www.ncbi.nlm.nih.gov/pubmed/34418435
http://dx.doi.org/10.1016/j.jbc.2021.101095