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Retinal Degeneration Caused by Ago2 Disruption

PURPOSE: Argonaute proteins are key players in small RNA-guided gene silencing processes. Ago2 is the member of the Argonaute subfamily with slicer endonuclease activity and is critical for microRNA homeostasis and indispensable for biological development. However, the impact of Ago2 dysregulation i...

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Detalles Bibliográficos
Autores principales: Chen, Xue-Jiao, Zhang, Chang-Jun, Wang, Ya-Han, Jin, Zi-Bing
Formato: Online Artículo Texto
Lenguaje:English
Publicado: The Association for Research in Vision and Ophthalmology 2021
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8447045/
https://www.ncbi.nlm.nih.gov/pubmed/34529004
http://dx.doi.org/10.1167/iovs.62.12.14