PKR deficiency alleviates pulmonary hypertension via inducing inflammasome adaptor ASC inactivation

Pulmonary hypertension is a progressive fatal disease that currently has no specific therapeutic approaches. In this study, dsRNA-dependent protein kinase (PKR) was considered a candidate molecule in pulmonary hypertension. We demonstrated that PKR is activated in the endothelium of experimental pul...

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Detalles Bibliográficos
Autores principales: Li, Yapei, Li, Ying, Li, Lijun, Yin, Minghui, Wang, Jiangang, Li, Xiaohui
Formato: Online Artículo Texto
Lenguaje:English
Publicado: SAGE Publications 2021
Materias:
Original Research Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8447110/
https://www.ncbi.nlm.nih.gov/pubmed/34540200
http://dx.doi.org/10.1177/20458940211046156

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8447110/
https://www.ncbi.nlm.nih.gov/pubmed/34540200
http://dx.doi.org/10.1177/20458940211046156

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