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A hypolipoprotein sepsis phenotype indicates reduced lipoprotein antioxidant capacity, increased endothelial dysfunction and organ failure, and worse clinical outcomes

OBJECTIVE: Approximately one-third of sepsis patients experience poor outcomes including chronic critical illness (CCI, intensive care unit (ICU) stay > 14 days) or early death (in-hospital death within 14 days). We sought to characterize lipoprotein predictive ability for poor outcomes and contr...

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Detalles Bibliográficos
Autores principales: Guirgis, Faheem W., Black, Lauren Page, Henson, Morgan, Labilloy, Guillaume, Smotherman, Carmen, Hopson, Charlotte, Tfirn, Ian, DeVos, Elizabeth L., Leeuwenburgh, Christiaan, Moldawer, Lyle, Datta, Susmita, Brusko, Todd M., Hester, Alexis, Bertrand, Andrew, Grijalva, Victor, Arango-Esterhay, Alexander, Moore, Frederick A., Reddy, Srinivasa T.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BioMed Central 2021
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8447561/
https://www.ncbi.nlm.nih.gov/pubmed/34535154
http://dx.doi.org/10.1186/s13054-021-03757-5