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The hepatic senescence-associated secretory phenotype promotes hepatocarcinogenesis through Bcl3-dependent activation of macrophages

BACKGROUND: Liver cancer is one of the most common malignancies in the world with a poor prognosis. Hepatocellular carcinoma (HCC) is the most prevalent primary liver cancer, accounting for 80–90% of cases. The initiation and progression of HCC are closely associated with chronic liver inflammation....

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Detalles Bibliográficos
Autores principales: Huang, Yihua, Yang, Xue, Meng, Yan, Shao, Changchun, Liao, Jianping, Li, Fengwei, Li, Rong, Jing, Yingying, Huang, Aimin
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BioMed Central 2021
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8447591/
https://www.ncbi.nlm.nih.gov/pubmed/34530917
http://dx.doi.org/10.1186/s13578-021-00683-5