Cargando…
The hepatic senescence-associated secretory phenotype promotes hepatocarcinogenesis through Bcl3-dependent activation of macrophages
BACKGROUND: Liver cancer is one of the most common malignancies in the world with a poor prognosis. Hepatocellular carcinoma (HCC) is the most prevalent primary liver cancer, accounting for 80–90% of cases. The initiation and progression of HCC are closely associated with chronic liver inflammation....
Autores principales: | Huang, Yihua, Yang, Xue, Meng, Yan, Shao, Changchun, Liao, Jianping, Li, Fengwei, Li, Rong, Jing, Yingying, Huang, Aimin |
---|---|
Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
BioMed Central
2021
|
Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8447591/ https://www.ncbi.nlm.nih.gov/pubmed/34530917 http://dx.doi.org/10.1186/s13578-021-00683-5 |
Ejemplares similares
-
3,5,3′-Triiodothyronine–Loaded Liposomes Inhibit Hepatocarcinogenesis Via Inflammation-Associated Macrophages
por: Sun, Gangqi, et al.
Publicado: (2022) -
Cell senescence, the senescence-associated secretory phenotype, and cancers
por: Langhi Prata, Larissa G. P., et al.
Publicado: (2023) -
Senescence-activated enhancer landscape orchestrates the senescence-associated secretory phenotype in murine fibroblasts
por: Guan, Yiting, et al.
Publicado: (2020) -
Cellular senescence, senescence-associated secretory phenotype, and chronic kidney disease
por: Wang, Wen-Juan, et al.
Publicado: (2017) -
Senescence-associated secretory phenotype and its impact on oral immune homeostasis
por: Yue, Ziqi, et al.
Publicado: (2022)