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Reciprocal priming between receptor tyrosine kinases at recycling endosomes orchestrates cellular signalling outputs

Integration of signalling downstream of individual receptor tyrosine kinases (RTKs) is crucial to fine‐tune cellular homeostasis during development and in pathological conditions, including breast cancer. However, how signalling integration is regulated and whether the endocytic fate of single recep...

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Detalles Bibliográficos
Autores principales: Smith, Michael P, Ferguson, Harriet R, Ferguson, Jennifer, Zindy, Egor, Kowalczyk, Katarzyna M, Kedward, Thomas, Bates, Christian, Parsons, Joseph, Watson, Joanne, Chandler, Sarah, Fullwood, Paul, Warwood, Stacey, Knight, David, Clarke, Robert B, Francavilla, Chiara
Formato: Online Artículo Texto
Lenguaje:English
Publicado: John Wiley and Sons Inc. 2021
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8447605/
https://www.ncbi.nlm.nih.gov/pubmed/34086370
http://dx.doi.org/10.15252/embj.2020107182