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UBE2S promotes the progression and Olaparib resistance of ovarian cancer through Wnt/β-catenin signaling pathway

BACKGROUND: Ovarian cancer is the most lethal gynecologic malignancy worldwide. Olaparib, an inhibitor of poly (ADP-ribose) polymerase (PARP), is becoming widely used in ovarian cancer treatment. The overall survival of ovarian cancer has not been significantly changed over the past decades and ovar...

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Detalles Bibliográficos
Autores principales: Hu, Wenjing, Li, Min, Chen, Youguo, Gu, Xinxian
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BioMed Central 2021
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8447717/
https://www.ncbi.nlm.nih.gov/pubmed/34535173
http://dx.doi.org/10.1186/s13048-021-00877-y