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Enhanced target-specific delivery of docetaxel-loaded nanoparticles using engineered T cell receptors

For effective targeted therapy of cancer with chemotherapy-loaded nanoparticles (NPs), antigens that are selective for cancer cells should be targeted to minimise off-tumour toxicity. Human leukocyte antigens (HLAs) are attractive cancer targets as they can present peptides from tumour-selective pro...

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Detalles Bibliográficos
Autores principales: McDaid, William J., Lissin, Nikolai, Pollheimer, Ellen, Greene, Michelle, Leach, Adam, Smyth, Peter, Bossi, Giovanna, Longley, Daniel, Cole, David K., Scott, Christopher J.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: The Royal Society of Chemistry 2021
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8447836/
https://www.ncbi.nlm.nih.gov/pubmed/34533174
http://dx.doi.org/10.1039/d1nr04001d