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Excitation ratiometric chloride sensing in a standalone yellow fluorescent protein is powered by the interplay between proton transfer and conformational reorganization

Natural and laboratory-guided evolution has created a rich diversity of fluorescent protein (FP)-based sensors for chloride (Cl(−)). To date, such sensors have been limited to the Aequorea victoria green fluorescent protein (avGFP) family, and fusions with other FPs have unlocked ratiometric imaging...

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Detalles Bibliográficos
Autores principales: Chen, Cheng, Tutol, Jasmine N., Tang, Longteng, Zhu, Liangdong, Ong, Whitney S. Y., Dodani, Sheel C., Fang, Chong
Formato: Online Artículo Texto
Lenguaje:English
Publicado: The Royal Society of Chemistry 2021
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8447875/
https://www.ncbi.nlm.nih.gov/pubmed/34667546
http://dx.doi.org/10.1039/d1sc00847a