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Synthetic Pept-Ins as a Generic Amyloid-Like Aggregation-Based Platform for In Vivo PET Imaging of Intracellular Targets

[Image: see text] Amyloid-like aggregation of proteins is induced by short amyloidogenic sequence segments within a specific protein sequence resulting in self-assembly into β-sheets. We recently validated a technology platform in which synthetic amyloid peptides (“Pept-ins”) containing a specific a...

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Detalles Bibliográficos
Autores principales: Siemons, Maxime, Luyten, Kaat, Khodaparast, Ladan, Khodaparast, Laleh, Lecina, Joan, Claes, Filip, Gallardo, Rodrigo, Koole, Michel, Ramakers, Meine, Schymkowitz, Joost, Bormans, Guy, Rousseau, Frederic
Formato: Online Artículo Texto
Lenguaje:English
Publicado: American Chemical Society 2021
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8447941/
https://www.ncbi.nlm.nih.gov/pubmed/34487434
http://dx.doi.org/10.1021/acs.bioconjchem.1c00369