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Inhibitory Compounds Targeting Plasmodium falciparum Gyrase B

Malaria persists as a major health problem due to the spread of drug resistance and the lack of effective vaccines. DNA gyrase is a well-validated and extremely effective therapeutic target in bacteria, and it is also known to be present in the apicoplast of malarial species, including Plasmodium fa...

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Detalles Bibliográficos
Autores principales: Pakosz, Zuzanna, Lin, Ting-Yu, Michalczyk, Elizabeth, Nagano, Soshichiro, Heddle, Jonathan Gardiner
Formato: Online Artículo Texto
Lenguaje:English
Publicado: American Society for Microbiology 2021
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8448092/
https://www.ncbi.nlm.nih.gov/pubmed/34339271
http://dx.doi.org/10.1128/AAC.00267-21