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Inhibitory Compounds Targeting Plasmodium falciparum Gyrase B
Malaria persists as a major health problem due to the spread of drug resistance and the lack of effective vaccines. DNA gyrase is a well-validated and extremely effective therapeutic target in bacteria, and it is also known to be present in the apicoplast of malarial species, including Plasmodium fa...
Autores principales: | Pakosz, Zuzanna, Lin, Ting-Yu, Michalczyk, Elizabeth, Nagano, Soshichiro, Heddle, Jonathan Gardiner |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
American Society for Microbiology
2021
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8448092/ https://www.ncbi.nlm.nih.gov/pubmed/34339271 http://dx.doi.org/10.1128/AAC.00267-21 |
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