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A Transposon-Associated CRISPR/Cas9 System Specifically Eliminates both Chromosomal and Plasmid-Borne mcr-1 in Escherichia coli

The global spread of antimicrobial-resistant bacteria has been one of the most severe threats to public health. The emergence of the mcr-1 gene has posed a considerable threat to antimicrobial medication since it deactivates one last-resort antibiotic, colistin. There have been reports regarding the...

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Detalles Bibliográficos
Autores principales: He, Yu-Zhang, Yan, Jin-Ru, He, Bing, Ren, Hao, Kuang, Xu, Long, Teng-Fei, Chen, Cai-Ping, Liao, Xiao-Ping, Liu, Ya-Hong, Sun, Jian
Formato: Online Artículo Texto
Lenguaje:English
Publicado: American Society for Microbiology 2021
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8448152/
https://www.ncbi.nlm.nih.gov/pubmed/34339270
http://dx.doi.org/10.1128/AAC.01054-21