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A Transposon-Associated CRISPR/Cas9 System Specifically Eliminates both Chromosomal and Plasmid-Borne mcr-1 in Escherichia coli
The global spread of antimicrobial-resistant bacteria has been one of the most severe threats to public health. The emergence of the mcr-1 gene has posed a considerable threat to antimicrobial medication since it deactivates one last-resort antibiotic, colistin. There have been reports regarding the...
Autores principales: | He, Yu-Zhang, Yan, Jin-Ru, He, Bing, Ren, Hao, Kuang, Xu, Long, Teng-Fei, Chen, Cai-Ping, Liao, Xiao-Ping, Liu, Ya-Hong, Sun, Jian |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
American Society for Microbiology
2021
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8448152/ https://www.ncbi.nlm.nih.gov/pubmed/34339270 http://dx.doi.org/10.1128/AAC.01054-21 |
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