The inhibitory effects of toothpaste and mouthwash ingredients on the interaction between the SARS-CoV-2 spike protein and ACE2, and the protease activity of TMPRSS2 in vitro

SARS-CoV-2 enters host cells when the viral spike protein is cleaved by transmembrane protease serine 2 (TMPRSS2) after binding to the host angiotensin-converting enzyme 2 (ACE2). Since ACE2 and TMPRSS2 are expressed in the tongue and gingival mucosa, the oral cavity is a potential entry point for S...

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Detalles Bibliográficos
Autores principales: Tateyama-Makino, Riho, Abe-Yutori, Mari, Iwamoto, Taku, Tsutsumi, Kota, Tsuji, Motonori, Morishita, Satoru, Kurita, Kei, Yamamoto, Yukio, Nishinaga, Eiji, Tsukinoki, Keiichi
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Public Library of Science 2021
Materias:
Research Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8448299/
https://www.ncbi.nlm.nih.gov/pubmed/34534255
http://dx.doi.org/10.1371/journal.pone.0257705

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8448299/
https://www.ncbi.nlm.nih.gov/pubmed/34534255
http://dx.doi.org/10.1371/journal.pone.0257705

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