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The late endosome-resident lipid bis(monoacylglycero)phosphate is a cofactor for Lassa virus fusion

Arenavirus entry into host cells occurs through a low pH-dependent fusion with late endosomes that is mediated by the viral glycoprotein complex (GPC). The mechanisms of GPC-mediated membrane fusion and of virus targeting to late endosomes are not well understood. To gain insights into arenavirus fu...

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Detalles Bibliográficos
Autores principales: Markosyan, Ruben M., Marin, Mariana, Zhang, You, Cohen, Fredric S., Melikyan, Gregory B.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Public Library of Science 2021
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8448326/
https://www.ncbi.nlm.nih.gov/pubmed/34492091
http://dx.doi.org/10.1371/journal.ppat.1009488