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Multiscale model of defective interfering particle replication for influenza A virus infection in animal cell culture

Cell culture-derived defective interfering particles (DIPs) are considered for antiviral therapy due to their ability to inhibit influenza A virus (IAV) production. DIPs contain a large internal deletion in one of their eight viral RNAs (vRNAs) rendering them replication-incompetent. However, they c...

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Detalles Bibliográficos
Autores principales: Rüdiger, Daniel, Pelz, Lars, Hein, Marc D., Kupke, Sascha Y., Reichl, Udo
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Public Library of Science 2021
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8448327/
https://www.ncbi.nlm.nih.gov/pubmed/34491996
http://dx.doi.org/10.1371/journal.pcbi.1009357