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Multiscale model of defective interfering particle replication for influenza A virus infection in animal cell culture
Cell culture-derived defective interfering particles (DIPs) are considered for antiviral therapy due to their ability to inhibit influenza A virus (IAV) production. DIPs contain a large internal deletion in one of their eight viral RNAs (vRNAs) rendering them replication-incompetent. However, they c...
| Autores principales: | , , , , |
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| Formato: | Online Artículo Texto |
| Lenguaje: | English |
| Publicado: |
Public Library of Science
2021
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| Materias: | |
| Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8448327/ https://www.ncbi.nlm.nih.gov/pubmed/34491996 http://dx.doi.org/10.1371/journal.pcbi.1009357 |