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Kaposi’s sarcoma-associated herpesvirus promotes mesenchymal-to-endothelial transition by resolving the bivalent chromatin of PROX1 gene

Increasing evidence suggests that Kaposi’s sarcoma (KS) arises from Kaposi’s sarcoma-associated herpesvirus (KSHV)-infected mesenchymal stem cells (MSCs) through mesenchymal-to-endothelial transition (MEndT). KSHV infection promotes MSC differentiation of endothelial lineage and acquisition of tumor...

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Detalles Bibliográficos
Autores principales: Ding, Yao, Chen, Weikang, Lu, Zhengzhou, Wang, Yan, Yuan, Yan
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Public Library of Science 2021
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8448337/
https://www.ncbi.nlm.nih.gov/pubmed/34492084
http://dx.doi.org/10.1371/journal.ppat.1009847