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Co-treatment With Everolimus, an mTOR-Specific Antagonist, or Downregulation of ELK1 Enhances the Sensitivity of Pancreatic Cancer Cells to Genistein

Genistein is a natural isoflavone with pharmacological or potentially anti-tumor properties. However, the resistance of cancer cells to genistein remains a major obstacle. This study focused on the mechanism implicated in the resistance of pancreatic cancer (PC) cells to genistein and the mechanism...

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Detalles Bibliográficos
Autores principales: Li, Tianyu, Kuang, Tiantao, Yang, Zhaoshuo, Zhang, Qiqi, Zhang, Wen, Fan, Yue
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Frontiers Media S.A. 2021
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8448347/
https://www.ncbi.nlm.nih.gov/pubmed/34540820
http://dx.doi.org/10.3389/fcell.2021.633035