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Comparing mutational pathways to lopinavir resistance in HIV-1 subtypes B versus C

Although combination antiretroviral therapies seem to be effective at controlling HIV-1 infections regardless of the viral subtype, there is increasing evidence for subtype-specific drug resistance mutations. The order and rates at which resistance mutations accumulate in different subtypes also rem...

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Detalles Bibliográficos
Autores principales: Posada-Céspedes, Susana, Van Zyl, Gert, Montazeri, Hesam, Kuipers, Jack, Rhee, Soo-Yon, Kouyos, Roger, Günthard, Huldrych F., Beerenwinkel, Niko
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Public Library of Science 2021
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8448360/
https://www.ncbi.nlm.nih.gov/pubmed/34491984
http://dx.doi.org/10.1371/journal.pcbi.1008363