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Novel Paracrine Action of Endothelium Enhances Glucose Uptake in Muscle and Fat

RATIONALE: A hallmark of type 2 diabetes is insulin resistance, which leads to increased endothelial cell (EC) production of superoxide and a simultaneous reduction in the availability of the vasoprotective signaling radical NO. We recently demonstrated in preclinical models that type 2 diabetes sim...

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Detalles Bibliográficos
Autores principales: Viswambharan, Hema, Yuldasheva, Nadira Y., Imrie, Helen, Bridge, Katherine, Haywood, Natalie J., Skromna, Anna, Hemmings, Karen E., Clark, Emily R., Gatenby, V. Kate, Cordell, Paul, Simmons, Katie J., Makava, Natallia, Abudushalamu, Yilizila, Endesh, Naima, Brown, Jane, Walker, Andrew M.N., Futers, Simon T., Porter, Karen E., Cubbon, Richard M., Naseem, Khalid, Shah, Ajay M., Beech, David J., Wheatcroft, Stephen B., Kearney, Mark T., Sukumar, Piruthivi
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Lippincott Williams & Wilkins 2021
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8448413/
https://www.ncbi.nlm.nih.gov/pubmed/34420367
http://dx.doi.org/10.1161/CIRCRESAHA.121.319517