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Combined exposure to polychlorinated biphenyls and high-fat diet modifies the global epitranscriptomic landscape in mouse liver

Exposure to a single dose of polychlorinated biphenyls (PCBs) and a 12-week high-fat diet (HFD) results in nonalcoholic steatohepatitis (NASH) in mice by altering intracellular signaling and inhibiting epidermal growth factor receptor signaling. Post-transcriptional chemical modification (PTM) of RN...

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Detalles Bibliográficos
Autores principales: Klinge, Carolyn M, Piell, Kellianne M, Petri, Belinda J, He, Liqing, Zhang, Xiang, Pan, Jianmin, Rai, Shesh N, Andreeva, Kalina, Rouchka, Eric C, Wahlang, Banrida, Beier, Juliane I, Cave, Matthew C
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Oxford University Press 2021
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8448424/
https://www.ncbi.nlm.nih.gov/pubmed/34548932
http://dx.doi.org/10.1093/eep/dvab008