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Massively parallel quantification of phenotypic heterogeneity in single-cell drug responses

Single-cell analysis tools have made substantial advances in characterizing genomic heterogeneity; however, tools for measuring phenotypic heterogeneity have lagged due to the increased difficulty of handling live biology. Here, we report a single-cell phenotyping tool capable of measuring image-bas...

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Detalles Bibliográficos
Autores principales: Yellen, Benjamin B., Zawistowski, Jon S., Czech, Eric A., Sanford, Caleb I., SoRelle, Elliott D., Luftig, Micah A., Forbes, Zachary G., Wood, Kris C., Hammerbacher, Jeff
Formato: Online Artículo Texto
Lenguaje:English
Publicado: American Association for the Advancement of Science 2021
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8448449/
https://www.ncbi.nlm.nih.gov/pubmed/34533995
http://dx.doi.org/10.1126/sciadv.abf9840