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The prevalence and specificity of local protein synthesis during neuronal synaptic plasticity

To supply proteins to their vast volume, neurons localize mRNAs and ribosomes in dendrites and axons. While local protein synthesis is required for synaptic plasticity, the abundance and distribution of ribosomes and nascent proteins near synapses remain elusive. Here, we quantified the occurrence o...

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Detalles Bibliográficos
Autores principales: Sun, Chao, Nold, Andreas, Fusco, Claudia M., Rangaraju, Vidhya, Tchumatchenko, Tatjana, Heilemann, Mike, Schuman, Erin M.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: American Association for the Advancement of Science 2021
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8448450/
https://www.ncbi.nlm.nih.gov/pubmed/34533986
http://dx.doi.org/10.1126/sciadv.abj0790