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Targeting lysophospholipid acid receptor 1 and ROCK kinases promotes antiviral innate immunity

Growing evidence indicates the vital role of lipid metabolites in innate immunity. The lipid lysophosphatidic acid (LPA) concentrations are enhanced in patients upon HCV or SARS-CoV-2 infection, but the function of LPA and its receptors in innate immunity is largely unknown. Here, we found that vira...

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Detalles Bibliográficos
Autores principales: Zhang, Chi, Li, Weiyun, Lei, Xiaobo, Xie, Zhenfei, Qi, Linlin, Wang, Hui, Xiao, Xia, Xiao, Jun, Zheng, Yuxiao, Dong, Chen, Zheng, Xin, Chen, Shiyang, Chen, Jianfeng, Sun, Bing, Qin, Jun, Zhai, Qiwei, Li, Jinsong, Wei, Bin, Wang, Jianwei, Wang, Hongyan
Formato: Online Artículo Texto
Lenguaje:English
Publicado: American Association for the Advancement of Science 2021
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8448453/
https://www.ncbi.nlm.nih.gov/pubmed/34533996
http://dx.doi.org/10.1126/sciadv.abb5933