Endothelial pannexin 1–TRPV4 channel signaling lowers pulmonary arterial pressure in mice

Pannexin 1 (Panx1), an ATP-efflux pathway, has been linked with inflammation in pulmonary capillaries. However, the physiological roles of endothelial Panx1 in the pulmonary vasculature are unknown. Endothelial transient receptor potential vanilloid 4 (TRPV4) channels lower pulmonary artery (PA) con...

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Detalles Bibliográficos
Autores principales: Daneva, Zdravka, Ottolini, Matteo, Chen, Yen Lin, Klimentova, Eliska, Kuppusamy, Maniselvan, Shah, Soham A, Minshall, Richard D, Seye, Cheikh I, Laubach, Victor E, Isakson, Brant E, Sonkusare, Swapnil K
Formato: Online Artículo Texto
Lenguaje:English
Publicado: eLife Sciences Publications, Ltd 2021
Materias:
Biochemistry and Chemical Biology
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8448527/
https://www.ncbi.nlm.nih.gov/pubmed/34490843
http://dx.doi.org/10.7554/eLife.67777

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8448527/
https://www.ncbi.nlm.nih.gov/pubmed/34490843
http://dx.doi.org/10.7554/eLife.67777

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