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Long non-coding RNA nuclear paraspeckle assembly transcript 1 regulates ionizing radiation-induced pyroptosis via microRNA-448/gasdermin E in colorectal cancer cells

Pyroptosis is mediated by gasdermins and serves a critical role in ionizing radiation (IR)-induced damage in normal tissues, but its role in cancer radiotherapy and underlying mechanisms remains unclear. Long non-coding (lnc) RNAs serve important roles in regulating the radiosensitivity of cancer ce...

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Detalles Bibliográficos
Autores principales: Su, Fei, Duan, Junzhao, Zhu, Jie, Fu, Hanjiang, Zheng, Xiaofei, Ge, Changhui
Formato: Online Artículo Texto
Lenguaje:English
Publicado: D.A. Spandidos 2021
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8448542/
https://www.ncbi.nlm.nih.gov/pubmed/34476497
http://dx.doi.org/10.3892/ijo.2021.5259