Cargando…

Long non-coding RNA nuclear paraspeckle assembly transcript 1 regulates ionizing radiation-induced pyroptosis via microRNA-448/gasdermin E in colorectal cancer cells

Pyroptosis is mediated by gasdermins and serves a critical role in ionizing radiation (IR)-induced damage in normal tissues, but its role in cancer radiotherapy and underlying mechanisms remains unclear. Long non-coding (lnc) RNAs serve important roles in regulating the radiosensitivity of cancer ce...

Descripción completa

Detalles Bibliográficos
Autores principales:	Su, Fei, Duan, Junzhao, Zhu, Jie, Fu, Hanjiang, Zheng, Xiaofei, Ge, Changhui
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	D.A. Spandidos 2021
Materias:	Articles
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8448542/ https://www.ncbi.nlm.nih.gov/pubmed/34476497 http://dx.doi.org/10.3892/ijo.2021.5259

Ejemplares similares

The role of long non-coding RNA (lncRNA) nuclear paraspeckle assembly transcript 1 (NEAT1) in chronic periodontitis progression
por: Zhang, Lei, et al.
Publicado: (2022)

Gasdermin D in pyroptosis
por: Burdette, Brandon E., et al.
Publicado: (2021)

Paraspeckles: nuclear bodies built on long noncoding RNA
por: Bond, Charles S., et al.
Publicado: (2009)

Paraspeckles modulate the intranuclear distribution of paraspeckle-associated Ctn RNA
por: Anantharaman, Aparna, et al.
Publicado: (2016)

Downregulation of Long Non-coding RNA Nuclear Paraspeckle Assembly Transcript 1 Inhibits MEG-01 Differentiation and Platelet-Like Particles Activity
por: Bian, Weihua, et al.
Publicado: (2020)

Novel pyroptosis-independent functions of gasdermins
por: Qin, Ziran, et al.
Publicado: (2022)

Pyroptosis, inflammasome, and gasdermins in tumor immunity
por: Ouyang, Xiaohu, et al.
Publicado: (2023)

RNA Profiling Reveals a Common Mechanism of Histone Gene Downregulation and Complementary Effects for Radioprotectants in Response to Ionizing Radiation
por: Ge, Changhui, et al.
Publicado: (2020)

Paraspeckle nuclear bodies—useful uselessness?
por: Nakagawa, Shinichi, et al.
Publicado: (2012)

Long non-coding RNA Neat1 and paraspeckle components are translational regulators in hypoxia
por: Godet, Anne-Claire, et al.
Publicado: (2022)

MicroRNA-448 modulates the progression of neuropathic pain by targeting sirtuin 1
por: Chu, Yunchao, et al.
Publicado: (2019)

Integrator restrains paraspeckles assembly by promoting isoform switching of the lncRNA NEAT1
por: Barra, Jasmine, et al.
Publicado: (2020)

Specific interaction with the nuclear transporter importin α2 can modulate paraspeckle protein 1 delivery to nuclear paraspeckles
por: Major, Andrew T., et al.
Publicado: (2015)

Posttranslational and Therapeutic Control of Gasdermin-Mediated Pyroptosis and Inflammation
por: Fischer, Fabian A., et al.
Publicado: (2021)

An ancient defense mechanism: Conservation of gasdermin-mediated pyroptosis
por: Wang, Chengliang, et al.
Publicado: (2023)

Gasdermin D-mediated pyroptosis: mechanisms, diseases, and inhibitors
por: Dai, Zhen, et al.
Publicado: (2023)

Pyroptosis Modulators: New Insights of Gasdermins in Health and Disease
por: Allali-Boumara, Imane, et al.
Publicado: (2023)

Loss of polarity regulators initiates gasdermin-E-mediated pyroptosis in syncytiotrophoblasts
por: Patel, Khushali, et al.
Publicado: (2023)

Phosphorothioate oligonucleotides can displace NEAT1 RNA and form nuclear paraspeckle-like structures
por: Shen, Wen, et al.
Publicado: (2014)

Long Non-Coding RNA Nuclear Paraspeckle Assembly Transcript 1 (NEAT1)Relieves Sepsis-Induced Kidney Injury and Lipopolysaccharide (LPS)-Induced Inflammation in HK-2 Cells
por: Gao, Cheng, et al.
Publicado: (2020)

Pyroptosis inhibiting nanobodies block Gasdermin D pore formation
por: Kopp, Anja, et al.
Publicado: (2023)

Stress granules regulate stress-induced paraspeckle assembly
por: An, Haiyan, et al.
Publicado: (2019)

Paraspeckles are subpopulation-specific nuclear bodies that are not essential in mice
por: Nakagawa, Shinichi, et al.
Publicado: (2011)

Silencing of Long Non-Coding RNA (lncRNA) Nuclear Paraspeckle Assembly Transcript 1 (NEAT1) Protects PC-12 Cells from LPS-Induced Injury via Targeting miR-29a
por: Ban, Yunchao, et al.
Publicado: (2020)

Gasdermin D is an executor of pyroptosis and required for interleukin-1β secretion
por: He, Wan-ting, et al.
Publicado: (2015)

Downregulating Gasdermin D Reduces Severe Acute Pancreatitis Associated with Pyroptosis
por: Lin, Tianjiao, et al.
Publicado: (2021)

Prokaryotic gasdermins: ancestors of eukaryotic counterparts direct the pyroptosis and cell fates
por: Liu, Yingying, et al.
Publicado: (2022)

Arsenic trioxide induces gasdermin E mediated pyroptosis in astroglioma cells
por: Wang, Jingling, et al.
Publicado: (2020)

Caspase-11-Gasdermin D-Mediated Pyroptosis Is Involved in the Pathogenesis of Atherosclerosis
por: Jiang, Mengqing, et al.
Publicado: (2021)

Switching from Apoptosis to Pyroptosis: Gasdermin-Elicited Inflammation and Antitumor Immunity
por: Tsuchiya, Kohsuke
Publicado: (2021)

Porcine Gasdermin D Is a Substrate of Caspase-1 and an Executioner of Pyroptosis
por: Song, Yueyang, et al.
Publicado: (2022)

Role of Pyroptosis in Inflammatory Bowel Disease (IBD): From Gasdermins to DAMPs
por: Zhang, Shuxia, et al.
Publicado: (2022)

BI 2536 induces gasdermin E-dependent pyroptosis in ovarian cancer
por: Huo, Jianting, et al.
Publicado: (2022)

Bacillus cereus cytotoxin K triggers gasdermin D-dependent pyroptosis
por: Zhao, Yan, et al.
Publicado: (2022)

Impairing Gasdermin D-mediated pyroptosis is protective against retinal degeneration
por: Sekar, Rakshanya, et al.
Publicado: (2023)

Nuclear paraspeckles function in mediating gene regulatory and apoptotic pathways
por: Pisani, Gabriel, et al.
Publicado: (2019)

FDA-approved disulfiram inhibits pyroptosis by blocking gasdermin D pore formation
por: Hu, Jun Jacob, et al.
Publicado: (2020)

Gasdermin E deficiency attenuates acute kidney injury by inhibiting pyroptosis and inflammation
por: Xia, Weiwei, et al.
Publicado: (2021)

Oncolytic Parapoxvirus induces Gasdermin E-mediated pyroptosis and activates antitumor immunity
por: Lin, Jing, et al.
Publicado: (2023)

Duck gasdermin E is a substrate of caspase-3/-7 and an executioner of pyroptosis
por: Li, Hanqing, et al.
Publicado: (2023)

Cannot write session to /tmp/vufind_sessions/sess_34oabdccth9cgb43ivs97g3jo5