Alkylation of rabbit muscle creatine kinase surface methionine residues inhibits enzyme activity in vitro

Creatine kinase (CK) catalyzes the formation of phosphocreatine from adenosine triphosphate (ATP) and creatine. The highly reactive free cysteine residue in the active site of the enzyme (Cys(283)) is considered essential for the enzymatic activity. In previous studies we demonstrated that Cys(283)...

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Detalles Bibliográficos
Autores principales: Steinritz, Dirk, Lüling, Robin, Siegert, Markus, Mückter, Harald, Popp, Tanja, Reinemer, Peter, Gudermann, Thomas, Thiermann, Horst, John, Harald
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Springer Berlin Heidelberg 2021
Materias:
Molecular Toxicology
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8448711/
https://www.ncbi.nlm.nih.gov/pubmed/34396457
http://dx.doi.org/10.1007/s00204-021-03137-6

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8448711/
https://www.ncbi.nlm.nih.gov/pubmed/34396457
http://dx.doi.org/10.1007/s00204-021-03137-6

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