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Predicting the in vivo developmental toxicity of benzo[a]pyrene (BaP) in rats by an in vitro–in silico approach

Developmental toxicity testing is an animal-intensive endpoints in toxicity testing and calls for animal-free alternatives. Previous studies showed the applicability of an in vitro–in silico approach for predicting developmental toxicity of a range of compounds, based on data from the mouse embryoni...

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Detalles Bibliográficos
Autores principales: Wang, Danlei, Rietdijk, Maartje H., Kamelia, Lenny, Boogaard, Peter J., Rietjens, Ivonne M. C. M.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Springer Berlin Heidelberg 2021
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8448719/
https://www.ncbi.nlm.nih.gov/pubmed/34432120
http://dx.doi.org/10.1007/s00204-021-03128-7