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A phase 2, proof of concept, randomised controlled trial of berberine ursodeoxycholate in patients with presumed non-alcoholic steatohepatitis and type 2 diabetes

Non-alcoholic steatohepatitis is frequently associated with diabetes and may cause progressive liver disease. Current treatment options are limited. Here we report on a prospective, randomised, double-blind, placebo-controlled trial of two doses of HTD1801 (berberine ursodeoxycholate, an ionic salt...

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Detalles Bibliográficos
Autores principales: Harrison, Stephen A., Gunn, Nadege, Neff, Guy W., Kohli, Anita, Liu, Liping, Flyer, Abbey, Goldkind, Lawrence, Di Bisceglie, Adrian M.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group UK 2021
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8448729/
https://www.ncbi.nlm.nih.gov/pubmed/34535644
http://dx.doi.org/10.1038/s41467-021-25701-5